The Eagles suddenly face a must-win against the lowly Giants on Christmas Day after falling short to the Seahawks to suffer a third consecutive loss.
New York fell to New Orleans 24-6 in Week 15 to snap a three-game winning streak, though Philadelphia should have no problem taking care of business against a divisional bottom-feeder.
In fact, oddsmakers expect a dominant blowout led by a strong defensive effort. Let's take a look at the opening odds to see how sportsbooks see this matchup playing out.
Giants vs. Eagles Week 16 Opening Odds
The Eagles are gigantic favorites with -550 odds on the moneyline and a 10.5-point spread. With a total set at 43, oddsmakers predict a score somewhere in the neighborhood of 26-16.
Philadelphia has three straight wins over New York, though the Giants have been notably scrappier under rookie QB Tommy Devito. They're 3-1 against the spread (ATS) in their last four contests but are 2-6 ATS in their previous eight on the road.
On the other side, the Eagles failed to cover each of their last three contests and need to get back in the win column. The offense put up just 30 points combined over the last two weeks but Philly is a strong home team, going 3-1 ATS in its previous four.
If you prefer a bet on the total, the over is 5-1 in the Eagles' last six at home and 3-2 in the Giants' last five overall, so we could have a high-scoring game in store.
Things have been rough for the Eagles over the last few weeks, but it's hard not to see this as a get-right spot. The G-Men have won two of their last three, but they still rank dead last in the NFL in point differential, getting out-scored by an average margin of 10.6 points per game. The Eagles, even with their recent struggles, still rank 11th in that category.
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Game odds refresh periodically and are subject to change.